From heteroplasmy shift to direct base correction: mitochondrial genome editing for disease modeling and therapy

Related

• bioRxiv·2 Oct 2026

  Early-life mitochondrial DNA mutations drive age-related pathology in mice

  

• Nature Communications·2 Oct 2026

  Base editing of the lamin farnesylation motif rescues progeria phenotypes in organoids

• Advanced Functional Materials·8 Oct 2026

  Mitochondrial transfer restored bone structure in animals

  

• bioRxiv·5 Oct 2026

  Gut microbes fuel aging tied to mitochondrial defects in mice