InterventionsHuman trial65 participantsNon-randomised trial

Nisotirostide (LY3457263), a novel NPY2 receptor agonist for type 2 diabetes and obesity: From discovery to clinical proof of concept

Molecular Metabolism

The paper

Daniel A. Briere, Jennifer K. Leohr, Helle Linnebjerg,
Show 9 more authorsAvinash Muppidi, Meghan P. Antonellis, Patrick Antonellis, Todd M. Suter, Elizabeth Smith LaBell, Daniel Lopes, Mridula Dogra, Tamer Coşkun, Jorge Alsina‐Fernandez,
Kieren J. Mather

Eli Lilly (United States)

Molecular Metabolism · 3 Oct 2026

doi.org/10.1016/j.molmet.2026.102452PubMed 42829171