The APOE4-estrogen-microglia axis in perimenopausal cognitive changes: mechanisms and therapeutic implications

Figure 1. Schematic overview of the APOE4-estrogen-microglia axis in perimenopausal cognitive vulnerability.
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Figure 1. Schematic overview of the APOE4-estrogen-microglia axis in perimenopausal cognitive vulnerability.Schematic overview of the APOE4-estrogen-microglia axis in perimenopausal cognitive vulnerability.Shi et al.

Frontiers in Immunology

The paper

Liaoning University of Traditional Chinese Medicine

Frontiers in Immunology · 20 Aug 2026

doi.org/10.3389/fimmu.2026.1925850PubMed 42694561