Skip to content
AgingResearch.News
  • HomeHome
  • SearchSearch
  • AskAsk
  • FollowingFollowing
  • SavedSaved
AgingResearch.News
Ageing Research Reviews

The Grandmother Hypothesis: A perspective from cardiovascular aging

By Weiguo Zhang
Graphical abstract from Ageing Research Reviews
Open the figure at full size
Graphical abstract. Zhang
ReviewMechanisms
Paper
  • Hormone replacement therapy
  • Modelling and theory
  • Sex hormone signalling (oestrogen, androgen)
  • Cardiovascular disease
  • Humans

The paper

Weiguo Zhang

Las Colinas Institutes

Ageing Research Reviews, 24 Aug 2026

doi.org/10.1016/j.arr.2026.103334PubMed 42637013

More on Sex hormone signalling (oestrogen, androgen)

  • Maturitas·4 Oct 2026

    Oestradiol levels do not predict heart events in older women

  • JCI Insight·6 Oct 2026

    Insulin resistance rose faster around menopause

  • The Journal of Clinical Endocrinology and Metabolism·5 Oct 2026

    Hypothalamic amenorrhea in mid-adulthood linked to heart disease

  • Menopause·4 Oct 2026

    Premature ovarian failure and depression linked to higher mortality

PrivacyTermsContact© 2026 AgingResearch.News

    News

    See all
    ER-100 glaucoma trial findings support testing higher dosesTrialsLongevity.Technology and 3 moreNew immune cell map reveals how individual immune aging trajectories divergeResearchMedical Xpress and 2 moreNewer cohorts of older Europeans show slower intrinsic capacity lossResearchThe Lancet Healthy Longevity

    Trials

    See all
    AKG and Brain Health in AgingPhase 2Registered 6 Oct 2026, University of OklahomaSafety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)Phase 1Registered 2 Oct 2026, Vinmec Research Institute of Stem Cell and Gene TechnologyAI-Based Conversational Social Support for Older Adults With Heart FailureRegistered 7 Oct 2026, Chang Gung University of Science and Technology

    Trending

    See all
    Vitamin D deficiencyDiseaseSevere vitamin D deficiency is linked to higher death rates, and 1 more story this weekKetogenic dietInterventionKetogenic diet improved heart function in aged miceNicotinamide ribosideInterventionNicotinamide riboside did not improve early Parkinson diseaseTERTGeneBlood-cell telomerase delays premature aging in zebrafishPregnancyInterventionEstimated brain-age gap rises by three years in pregnancyChildhood lonelinessInterventionChildhood loneliness linked to faster frailty progression

    Topics

    See all
    Mechanisms253Interventions435Biomarkers421Populations560AI & data168Industry & policy18
    • Privacy
    • Terms
    • Contact
    • © 2026 AgingResearch.News