Skip to content
AgingResearch.News
  • HomeHome
  • SearchSearch
  • AskAsk
  • FollowingFollowing
  • SavedSaved
AgingResearch.News
PNAS

AAV-NRF2 protects retinal and choroidal vasculature in a GDF15-dependent manner in an oxidative damage model of AMD

By Shuai Wang, Sophia Zhao, Adam Daniels, +3Show 3 more authors, Constance L. Cepko
Experiments in animalsInterventions
Paper

The paper

Shuai Wang, Sophia Zhao, Adam Daniels, +3Show 3 more authors, Efrat Naaman, Apolonia Gardner, Lois E. H. Smith, Constance L. Cepko

Howard Hughes Medical Institute

PNAS, 11 Aug 2026

doi.org/10.1073/pnas.2616985123PubMed 42579492

Related

  • bioRxiv·2 Oct 2026

    Engineered cardiac transcription factor restores vision and reduces frailty in aging mice

  • bioRxiv·9 Oct 2026

    Aging alters eye tissue proteins differently in mice

  • International Journal of Molecular Sciences·2 Oct 2026

    Targeted metal modulation preserves retinal structure and vision in zebrafish

  • bioRxiv·2 Oct 2026

    Macrophage-derived VEGFA maintains eye outflow in mice

PrivacyTermsContact© 2026 AgingResearch.News

    News

    See all
    ER-100 glaucoma trial findings support testing higher dosesTrialsLongevity.Technology and 3 moreNew immune cell map reveals how individual immune aging trajectories divergeResearchMedical Xpress and 2 moreNewer cohorts of older Europeans show slower intrinsic capacity lossResearchThe Lancet Healthy Longevity

    Trials

    See all
    AKG and Brain Health in AgingPhase 2Registered 6 Oct 2026, University of OklahomaSafety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)Phase 1Registered 2 Oct 2026, Vinmec Research Institute of Stem Cell and Gene TechnologyAI-Based Conversational Social Support for Older Adults With Heart FailureRegistered 7 Oct 2026, Chang Gung University of Science and Technology

    Trending

    See all
    Vitamin D deficiencyDiseaseSevere vitamin D deficiency is linked to higher death rates, and 1 more story this weekKetogenic dietInterventionKetogenic diet improved heart function in aged miceNicotinamide ribosideInterventionNicotinamide riboside did not improve early Parkinson diseaseTERTGeneBlood-cell telomerase delays premature aging in zebrafishPregnancyInterventionEstimated brain-age gap rises by three years in pregnancyChildhood lonelinessInterventionChildhood loneliness linked to faster frailty progression

    Topics

    See all
    Mechanisms253Interventions435Biomarkers421Populations560AI & data165Industry & policy18
    • Privacy
    • Terms
    • Contact
    • © 2026 AgingResearch.News