Nature
FNIP1 variants are associated with favourable metabolism in 1 million humans
By George Hindy, Rene C. Adam, Olukayode Ayodeji Sosina, +370Show 370 more authors, Luca Andrea Lotta
Genetic association study in peopleMechanisms
The paper
George Hindy, Rene C. Adam, Olukayode Ayodeji Sosina, +370Show 370 more authors, Dwaine S. Pryce, David Blair, Joseph Herman, Joseph Lee, Peter Dornbos, Ernst Mayerhofer, Arthur Gilly, Charleen Hunt, Benjamin Geraghty, Karl Landheer, Liron Ganel, Antoine Baldassari, Chuanyi Zhang, Ivory J. Mintah, Daphne Sun, Angel Coppola, Kyle Brown, Tram Nguyen, Xin Xia, Andrew Deubler, Adolfo Ferrando, Giovanni Coppola, Alan Shuldiner, Katherine Siminovitch, Jason Portnoy, Lyndon Mitnaul, Alison Fenney, Manuel Allen Revez Ferreira, Maya Ghoussaini, Mona Nafde, William Salerno, Lourdes Crane, Christina Beechert, Erin Fuller, Laura M. Cremona, Eugene Kalyuskin, Hang Du, Caitlin Forsythe, Zhenhua Gu, Kristy Guevara, Michael Lattari, Alexander Lopez, Kia Manoochehri, Prathyusha Challa, Manasi Pradhan, Raymond Reynoso, Ricardo Schiavo, Maria Sotiropoulos Padilla, Chenggu Wang, Sarah E. Wolf, Manan Goyal, George Mitra, Sanjay Sreeram, Rouel Lanche, Vrushali Mahajan, Sai Lakshmi Vasireddy, Gisu Eom, Krishna Pawan Punuru, Sujit Gokhale, Benjamin Sultan, Pooja Mule, Mudasar Sarwar, Muhammad Aqeel, Xiaodong Bai, Lance Zhang, Sean O’Keeffe, Razvan Panea, Evan Edelstein, Ayesha Rasool, Evan K. Maxwell, Boris Boutkov, Alexander Gorovits, Ju Guan, Lukas Habegger, Alicia Hawes, Olga Krasheninina, Samantha Zarate, Adam J. Mansfield, Joshua Backman, Kathy Burch, Adrián Campos, Sheila Gaynor, Arkopravo Ghosh, Salvador Romero Martinez, Christopher Gillies, Lauren Gurski, Eric Jorgenson, Tyler Joseph, Michael Kessler, Jack Kosmicki, Priyanka Nakka, Olivier Delaneau, Anthony Marcketta, Joelle S. Mbatchou, Arden Moscati, Anita Pandit, Jonathan Ross, Carlo Sidore, Eli Stahl, Timothy Thornton, Sailaja Vedantam, Rujin Wang, Kuan-Han Wu, Bin Ye, Blair Zhang, Andrey Ziyatdinov, Yuxin Zou, Jingning Zhang, Kyoko Watanabe, Mira Tang, Frank Wendt, Suying Bao, Kathie Sun, Sean Yu, Aaron Zhang, David Corrigan, Dhruv Shidhaye, Chen Wang, Keyrun Adhikari, Alexander Lachmann, Mark Weiner, Brian Hobbs, Jon Silver, William Palmer, Rita Guerreiro, Amit Joshi, Sarah Graham, Erola Pairó Castiñeira, Tanima De, Luanluan Sun, Mary Haas, Juan Rodriguez-Flores, Moeen Riaz, Manav Kapoor, Gannie Tzoneva, Momodou W. Jallow, Anna Alkelai, Ariane H. Ayer, Veera Rajagopal, Sahar Gelfman, Vijay Kumar, Jacqueline Otto, Jose Bras, Silvia Álvarez, Jessie Brown, Hossein Khiabanian, Joana Revez, Kimberly Skead, Valentina Zavala, Jae Soon Sul, Lei Chen, Sam Choi, Amy Damask, Nan Lin, Charles Paulding, Sameer Malhotra, Nadia Rana, Jennifer Rico-Varela, Jaimee Hernandez, Larizbeth Romero, Ashley Paynter, Randi Schwartz, Jody Hankins, Anna Han, Samuel Hart, Ryan Smith, Ann Perez-Beals, Gina Solari, Johannie Rivera-Picart, Michelle Pagan, Sunilbe Siceron, Adam Buchanan, David J. Carey, Christa L. Martin, Michelle Meyer, Kyle Retterer, David Rolston, Penn Medicine Biobank, Marylyn DeRiggi Ritchie, JoEllen Weaver, Nawar Naseer, Giorgio Sirugo, Afiya Poindexter, Yi-An Ko, Kyle P. Nerz, Jenna Dever, Aidan Harvey, Sydney Linn, Meghan Livingstone, Fred Vadivieso, Stephanie L. DerOhannessian, Teo Tran, Julia Stephanowski, Salma Santos, Ned Haubein, Joseph Dunn, Anurag Verma, Colleen Morse Kripke, Marjorie Risman, Renae Judy, Colin Wollack, Shefali S. Verma, Scott Damrauer, Yuki Bradford, Scott Dudek, Theodore Drivas, Heather D. Anderson, Christina L. Aquilante, Kelsey L. Arbogast, Ian M. Brooks, Elizabeth E. Burke, Emily M. Casteel, Joanne B. Cole, Curtis R. Coughlin, Jacob Crawford, Kristy Crooks, Erin Culver, Matthew J. Fisher, Teresa C. Frye, Hunter George, Chris R. Gignoux, Elizabeth K. Gilliland, Casey S. Greene, Emily C Hearst, Audrey E. Hendricks, Randi K. Johnson, Shelby Jones, Dave Kao, Gabrielle A. Knortz, Danielle Koffenberger, Santhanagopalan Krishnamoorthy, Lisa Ku, Elizabeth L. Kudron, Rashawnda Lacy, Ethan M. Lange, Joe A. Lesny, Meng Lin, James L. Martin, Adrian M. Stewart, Alaa Radwan, Anna Tanaka, Carolina Sanchez-Wild, Carolyn T. Swartz, Elise L. Shalowitz, Emily B. Todd, Hoda Sherif, Jack Pattee, Jonathan A. Shortt, Katy E. Trinkley, Laura K. Wiley, Neda Rasouli, Nick Rafaels, Nicole L. McDaniel, Nikita Pozdeyev, Sridharan Raghavan, Vendant Vohra, James R. Cerhan, Fergus J. Couch, Janet E. Olson, Nicholas Bradley Larson, Zachary S. Fredericksen, Mine Cicek, Joanna M. Biernacka, Victor M. Karpyak, Prashanthi Vemuri, Vijay K. Ramanan, Mark A. Frye, Sarah A. McLaughlin, Kathryn J. Ruddy, Suzette J. Bielinski, John C. Lieske, William Michael Hooten, Lisa A. Boardman, Richard B. Kennedy, Andrew D. Badley, Sean C. Dowdy, Jamie N. Bakkum-Gamez, Gretchen Elizabeth Glaser, Ping Yang, Celine M. Vachon, Angela A. Dispenzieri, Samuel O. Antwi, Ann L. Oberg, Kari G. Rabe, Scott H. Kaufmann, Ellen L. Goode, William A. Cliby, J. Eric Ahlskog, James H. Bower, Peter C. Harris, Naveen L. Pereira, Daniel J. Ma, Robert W. Mutter, Jeanette E. Eckel-Passow, Lisa K. Colborn, Andrew J. Danielsen, Jonathan J. Harrington, Jennifer M. Kushwaha, Mexico City Prospective Study, Malmö Diet and Cancer Study, Naga P. Chalasani, Tae-Hwi L.Schwantes-An, Andrew J. Saykin, Alex Bui, Antonia Petruse, Arash Naeim, Chris Denny, Clara Lajonchere, Clara Magyar, Dan Geschwind, Maryam Ariannejad, Paul Boutros, Paul Spellman, Sarah Dry, Stan Nelson, Albert Duntugan, Bogdan Paşaniuc, Paul Tung, Tim Chang, Yael Berkovich, Ankur Jain, Danielle Martinez, Ghouse Mohammed, Lora Illiev, Michael Broudy, Roni Haas, Shaiful Alam, Taka Yamaguchi, Yash Patel, Mount Sinai Million Health Discoveries Program, Alexander W. Charney, UTSW-Dallas Biobank, Julia Kozlitina, Jonathan Cohen, South Asia Biobank Study, Marie Loh, Prasad Katulanda, Vinitaa Jha, Anuradhani Kasturiratne, Khadija Irfan Khawaja, Malay Kanti Mridha, Ranjit Mohan Anjana, John Campbell Chambers, Daniel James Rader, Olle Melander, Christopher D. Still, Jaime Berumen-Campos, Pablo Antonio Kuri-Morales, Jesús Alegre-Díaz, Jason M. Torres, Jonathan R. Emberson, Rory Collins, Roberto Tapia-Conyer, Suganthi Balasubramanian, Marcus B. Jones, Michelle G. LeBlanc, Andrew J. Murphy, Christos A. Kyratsous, John D. Overton, Jeffrey G. Reid, Gonçalo R. Abecasis, Jonathan Marchini, Cristen J. Willer, George D. Yancopoulos, Mark W. Sleeman, Jonas Bovijn, Adam E. Locke, Aris Baras, Niek Verweij, Viktoria Gusarova, Luca Andrea Lotta
Regeneron (United States)
Nature, 5 Aug 2026
