Life Sciences

The role and mechanisms of RNA-binding proteins in the development of ovarian aging and related diseases

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Abstract

Ovarian aging is a key factor influencing female fertility and overall health. RNA-binding proteins (RBPs) regulate mRNA stability and translation, playing a significant role in maintaining ovarian function. This review discusses RBPs' involvement in oocyte development, folliculogenesis, and ovarian homeostasis. Additionally, we explore their roles in ovarian aging-related diseases and potential strategies for mitigating ovarian decline by targeting RBP activity. This review highlights RBPs' molecular mechanisms and potential applications for understanding and treating ovarian aging.