PLOS Biology

A somatic view of the genomic impact of mitochondrial endosymbiosis

CommentaryMechanisms
Follow

Abstract

The endosymbiosis of mitochondrial ancestors resulted in the transfer of genetic material on an evolutionary scale for eukaryotic species. A new study in PLOS Biology expands this to the genome of somatic cells within individuals and highlights its correlation with aging and disease.

The paper

University of Colorado Anschutz

PLOS Biology, Aug 23, 2024, Open access

doi.org/10.1371/journal.pbio.3002756PubMed 39178182