Zenodo

Predictive Bioharmonics: An Algorithmic Framework for the Analysis and Regulation of Biological Aging Dynamics

Preprint: computational studyBiomarkers
Follow

Abstract

Biological aging is typically attributed to time, genetics, or cumulative molecular damage. Here, aging is reframed as a dynamical process driven by the accumulation of internal instability (“drift”) beyond reversible regimes. Predictive Bioharmonics (PB) is introduced as a minimal algorithmic framework to detect, quantify, and regulate biological drift before irreversible transitions occur, using physiological regulation dynamics and targeted pre-instability adjustments. The paper presents a dynamical aging model and an empirical application of PB Test 2 (Drift & Recovery) on real human ECG-derived HRV data. Systems show distinct recovery behaviors after perturbation, with some rapidly returning to low-drift states while others exhibit prolonged instability. These results support aging-related decline as a function of recovery capacity rather than chronological time. No pharmaceuticals, invasive procedures, genetic modification, or advanced biotechnology are involved. All methods and pseudocode are provided for independent evaluation and replication.

The paper

Creator of Predictive Bioharmonics

Zenodo, 18 Dec 2025, Open access, CC BY, Preprint, not peer-reviewed

doi.org/10.5281/zenodo.17970222