Frontiers in Aging
Age-associated remodeling of NK cell subsets, B cell subsets, and T cell surface markers in peripheral blood of healthy Chinese adults: a prospective multicolor flow cytometry study

Cross-sectional study of 146 peopleMechanisms
Abstract
Background: Immunosenescence refers to the structural and functional remodeling of the immune system that accompanies aging, and is closely linked to increased susceptibility to infection, diminished vaccine responses, and a higher burden of chronic disease.
- Immune response
- CD28 expression in CD8+ T cells
- CD4+ CD57+ T cells
- CD56hiCD16− regulatory NK cells
- CD8+ CD57+ T cells
- Humans
The paper
Chinese Academy of Medical Sciences & Peking Union Medical College
Frontiers in Aging, 9 Oct 2026, CC BY



