CD28 expression in CD8+ T cells

Chronological age is associated with CD28 expression in CD8+ T cells in humans (r = −0.552).

“CD28 loss ( r = −0.552), and naive depletion ( r = −0.534) all reached p < 0.001.”

Humanshealthy Chinese adults; panel enriched for older participantsperipheral bloodn = 43

Age-associated remodeling of NK cell subsets, B cell subsets, and T cell surface markers in peripheral blood of healthy Chinese adults: a prospective multicolor flow cytometry study

Frontiers in aging·9 Oct 2026