Frontiers in Medicine

Poorer vision linked to long-term cardiovascular risk

Each 0.1-unit increase on a scale where higher scores mean worse vision was associated with a 5.7% higher relative risk of major cardiovascular events.

Paper by Bowen Zhang, Xindi Wang, Zizhu Lian et al.

A large partly obscured eye sits beside a heart with narrowed vessels, while a smaller clear eye sits near a heart with wider vessels.
Accepted, not yet published: cohort study of 111,446 people without major cardiovascular events at baseline, median 14.17 yearsBiomarkers

Dose-response

Limit: Vision’s added predictive value and usefulness in clinical care still need evaluation

Edited by Boris Djordjevic · AgingResearch.News

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The prospective cohort study included 111,446 people with vision measurements in both eyes and no major cardiovascular events at baseline. Their mean age was 56.67 years, and 55.4% were women. Researchers analyzed vision in each person’s better-seeing eye.

Over a median follow-up of 14.17 years, 8,275 first cardiovascular events occurred. These were heart attacks, heart failure, strokes caused by blocked blood flow, or deaths from cardiovascular disease. After accounting for demographic, lifestyle, socioeconomic and health factors, each 0.1-unit increase on the vision scale, indicating worse vision, was associated with a 5.7% higher relative risk. People in the poorest-vision quarter also had higher risk than those in the best-vision quarter.

Why it matters

Vision and cardiovascular health are closely linked to aging and functional decline. This work addresses whether a readily available measure of function could help identify cardiovascular vulnerability as people age.

Caveats

This observational study cannot establish cause and effect and excluded people with major cardiovascular events at baseline. The authors said vision’s added predictive value and usefulness in clinical care still need evaluation.

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