AHA Scientific Sessions 2026 Abstract

Frequent loneliness linked to more heart disease and stroke

Stroke prevalence was 7.3% among persistently lonely adults versus 2.7% among never-lonely adults in a national survey.

Paper by Yussif Issaka, Kwame Adjei-Sefah, Mohammad Maraqah, +3 more authorsStuart Zarich · Yale New Haven Health/Bridgeport Hosp
A brain with a dark damaged region sits beside a heart and separated gray people, opposite a healthy brain surrounded by a closer group of people.

Our read

Populations
Studied:
Cross-sectional study of 31,470 US adults, against never-lonely adults
What changed:
Stroke prevalence was higher among adults reporting persistent loneliness: 7.3% against 2.7% in never-lonely adults
The catch:
Heart disease or stroke may have contributed to loneliness rather than the reverse
Why it’s aging research:
It bears on staying healthy in midlife and later life.

Editor of record: Boris Djordjevic · AgingResearch.News

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Among 31,470 US adults in the 2024 National Health Interview Survey, researchers examined loneliness and disease prevalence in an observational analysis. They adjusted for age, sex, race and ethnicity, income and education.

Adults reporting persistent loneliness had higher prevalence of coronary heart disease, which affects the heart’s blood supply, than never-lonely adults: 8.0% versus 4.9%. Diabetes prevalence was 16.2% versus 9.8%, and high blood pressure prevalence was 37.5% versus 32.1%. More frequent loneliness was associated with greater disease burden even after adjustment. The researchers defined social isolation as loneliness at least sometimes combined with rarely or never having emotional support. Socially isolated adults had 71% higher adjusted stroke prevalence than socially connected adults.

Why it matters

Heart disease and stroke threaten health as people age. The authors suggested social connection as a potentially modifiable target for cardiovascular prevention.

Caveats

The survey assessed loneliness and existing disease, so heart disease or stroke may have contributed to loneliness rather than the reverse. The findings were reported in an AHA Scientific Sessions 2026 conference abstract.

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