Protective Effects of the FOXO3 Longevity Gene on Aging-Related Diseases in the CHAMP Cohort

Abstract

Recent findings from the Kuakini Honolulu Heart Program cohort in Hawaii suggest that longevity-associated gene variants of FOXO3 (e.g. SNP rs2802292-G allele carriers) may confer resilience against cardiometabolic diseases (CMD) such as hypertension, diabetes, and angina, in Japanese-American men.