PopulationsHumans
Causal Associations Between Major Depression and Accelerated Biological Aging.
GSA 2025 Abstract
Abstract
Over the past decades, there is growing evidence from clinical and epidemiological studies that history of major depression is associated with adverse health outcomes, including higher incidence of Alzheimer’s disease, cardiovascular diseases, and mortality.
- Major depressive disorder
- Brain-specific Proteomic Aging
- Healthspan proteomic score
- Proteomic aging clock
- Humans


