Using Drugs to Slow Aging in the Nematode Caenorhabditis Elegans

Abstract

With its 2-3 week lifespan, C. elegans is a convenient animal model for testing drug effects on aging. We have used liposome-mediated drug delivery to reduce confounding effects of interactions between drugs and the nematodes’ bacterial food source, improve compound uptake, and greatly reduce drug quantities needed for trials.