GSA 2025 Abstract

Parity Affects the Gut Microbiome, Gut Homeostasis, and Glucose Metabolism in Aged Female Mice

Experiments in animalsMechanisms

Abstract

Metabolic health declines with age. Parity, a history of prior reproduction, is implicated in regulating long-term metabolic health. Despite nearly 75% of women having a history of parity, virtually all preclinical studies use nulliparous mice, thus limiting the translation potential to improve women’s health.

The paper

Tufts University

GSA 2025 Abstract, 31 Dec 2025, CC BY

Presented at GSA 2025

doi.org/10.1093/geroni/igaf122.1796