DIETARY METHIONINE RESTRICTION STARTED LATE IN LIFE IMPROVES NEUROMUSCULAR FUNCTION AND PROMOTES HEALTHY AGING

Abstract

Methionine metabolism is negatively affected by aging and restricting methionine consumption (MetR) extends lifespan across diverse species. Similarly, levels of enzymes in the tyrosine degradation pathway (TDP) increase with age, the targeting of which extends Drosophila lifespan.