CALORIC RESTRICTION VERSUS TIME-RESTRICTED EATING: THE HEALTH, AGING, AND LATER-LIFE OUTCOMES PILOT

Abstract

In animal models, dietary interventions including caloric restriction (CR) and time-restricted eating (TRE) extend both lifespan and healthspan. However, in humans, the long-term benefits of these diets on lifespan and healthspan, and whether benefits outweigh harms, are unknown.