miR-20a-5p inhibition attenuates post-myocardial infarction ventricular remodeling in association with mTORC1/S6 signaling

Abstract

Maladaptive ventricular remodeling is the major pathological process linking myocardial infarction (MI) to heart failure, yet its upstream molecular drivers remain incompletely defined. Extracellular vesicle (EV)-enriched microRNAs (miRNAs) are emerging regulators of intercellular communication and cardiac pathology.

The paper