bioRxiv
Combination of ALK2 and cholesterol targeting agents exploits linked genetic and metabolic dependencies in diffuse midline glioma
Preprint: experiments in cellsInterventions
Abstract
Diffuse midline glioma is an epigenetically driven disease defined by alterations targeting the histone post-translational modification H3K27me3 resulting in epigenetic rewiring and imposing unique metabolic dependencies.
The paper
Institute of Cancer Research
bioRxiv, 23 Sep 2026, CC BY, Preprint, not peer-reviewed
