First Atom Therapeutics
CompanyUnited States
First Atom Therapeutics develops 2 assets, the furthest preclinical (ATX-091 in ischemia/stroke). Mostly small molecule acting on SARM1; based in the United States.
- 2
- Assets
- Furthest stage
- Preclinical
- 0
- Trials
- 0
- Signals
Pipeline
2Inhibits DRP1, targeting mitochondrial fragmentation.
Preclinical, Small molecule, ischemia/stroke, Parkinson's disease
Allosterically inhibits SARM1 by gluing two protein domains together, stabilizing its inactive structure.
Preclinical, Small molecule, SARM1, ADOA, amyotrophic lateral sclerosis
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- Evidence behind the mechanisms1
- People19
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