Visible light

Visible light has been studied in 5 papers since 2018: none in people yet, 3 in animals, 2 reviews; 1 in the past year. The research so far is in animals.

Intervention

5 papers study it7 findingsUpdated

See all 4 papers on visible light

At a glance

The findings reach worms or flies, none yet in people; independent labs found the same change in worms or flies. 3 independent labs in 3 countries.

None of its findings points the other way.

Worms or flies: replicated by independent labs. Cells, mice and humans: nothing yet.
  • 3 independent labs in 3 countries
  • Funders: American Federation for Aging Research and others
  • Model organisms3

What did studies of visible light find?

6

Studies of visible light measured 6 outcomes; the most studied are lifespan (2 studies), sleep time (1) and evening anticipation index (1).

Lifespan

downin flies1downin worms1

2 studies
  1. Visible light shortens lifespan in flies (Effect depended on dietary protein content).

    “visible light could be toxic to Drosophila survival, depending on the protein content in diet.”

    Model organismsEffect depended on dietary protein contentboth sexess

    Toxic Effect of Visible Light on Drosophila Life Span Depending on Diet Protein Content

    The journals of gerontology. Series A, Biological sciences and medical sciences

  2. Visible light shortens lifespan in worms.

    “C. elegans lifespan is inversely correlated to the time worms were exposed to visible light.”

    Model organismslow-intensity

    Visible light reduces C. elegans longevity

    Nature communications

Sleep time

no changein flies1

1 study
  1. Visible light showed no clear effect on sleep time in flies.

    “while there is no effect of colored light on the waking time, daily active time, and sleep time.”

    Model organisms

    Alterations in lifespan and sleep:wake duration under selective monochromes of visible light in Drosophila melanogaster

    Biology open

Evening anticipation index

upin flies1

1 study
  1. Visible light increases evening anticipation index in flies under blue and green light.

    “Significant increase in the evening anticipation index of flies under blue and green light alongside increased and decreased sleep depth during the day and night respectively suggests the light avoidance”

    Model organismsunder blue and green light

    Alterations in lifespan and sleep:wake duration under selective monochromes of visible light in Drosophila melanogaster

    Biology open

Locomotor activity

downin flies1

1 study
  1. Visible light decreases locomotor activity in flies under the light phase of blue and green light as compared to their dark phase.

    “significantly reduced activity levels under the light phase of blue and green light as compared to their dark phase is observed.”

    Model organismsunder the light phase of blue and green light as compared to their dark phase

    Alterations in lifespan and sleep:wake duration under selective monochromes of visible light in Drosophila melanogaster

    Biology open

ER unfolded protein response

upin worms1

1 study
  1. Visible light induces ER unfolded protein response in worms.

    “visible light creates photooxidative stress along with a general unfolded-protein response that decreases the lifespan.”

    Model organisms

    Visible light reduces C. elegans longevity

    Nature communications

More on ER unfolded protein response

Oxidative stress and ROS signaling

upin worms1

1 study
  1. Visible light induces oxidative stress and ROS signaling in worms.

    “visible light creates photooxidative stress along with a general unfolded-protein response that decreases the lifespan.”

    Model organisms

    Visible light reduces C. elegans longevity

    Nature communications

More on Oxidative stress and ROS signaling

Funding

1 grant since 2020

National Eye Institute$2.3M

Latest