Blue-blocking intraocular lens

Blue-blocking intraocular lens has been studied in 2 papers since 2017: 1 trial in people, 1 review. The newest paper, Jan 18, 2024: “Blue light and intraocular lenses (IOLs): Beliefs and realities”.

Intervention

2 papers study it4 findingsUpdated

See all 2 papers on blue-blocking intraocular lens

At a glance

The findings reach people, from one lab or study. 1 lab in 1 country.

“no significant difference was found between yellow and clear IOLs groups regarding sleep time, sleep latency, total sleep duration, quality of sleep”
Sleep and mood changes in advanced age after blue-blocking (yellow) intra ocular lens (IOLs) implantation during cataract surgical treatment: a randomized controlled trialAging & mental health2017doi:10.1080/13607863.2017.1348482

None of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 1 lab in 1 country
  • Funder: Ministère des Solidarités et de la Santé
  • Human trial1

Studies in people

1 study gave blue-blocking intraocular lens to people and measured what changed.

What changedDesignPeopleSource

no change: Has no effect on sleep

up: Raises the risk of depression13.1% vs 4.7%, p = 0.02

Randomized trial8 weeks204 peoplemean age 76.2 ± 7.5 yearsOlder adults; after bilateral cataract surgeryAging & mental health, Jul 10, 2017

What did studies of blue-blocking intraocular lens find?

3

Studies of blue-blocking intraocular lens measured 3 outcomes; the most studied are glare disability (1 study), age-related macular degeneration (1) and sleep (1).

Glare disability

no changein humans1

1 study
  1. Blue-blocking intraocular lens showed no clear effect on glare disability in humans.

    “Additionally, blue-filtering IOLs or spectacles cannot decrease glare disability, because they decrease image and glare illuminance in the same proportion.”

    Review

    Blue light and intraocular lenses (IOLs): Beliefs and realities

    Journal francais d'ophtalmologie

Age-related macular degeneration

no changein humans1

1 study
  1. Blue-blocking intraocular lens showed no clear effect on age-related macular degeneration in humans.

    “Very large epidemiological studies show that blue-blocking IOLs do not reduce the risk or progression of AMD.”

    Review

    Blue light and intraocular lenses (IOLs): Beliefs and realities

    Journal francais d'ophtalmologie

More on Age-related macular degeneration

Sleep

no changein humans1

1 study
  1. Blue-blocking intraocular lens showed no clear effect on sleep in humans after bilateral cataract surgery.

    “no significant difference was found between yellow and clear IOLs groups regarding sleep time, sleep latency, total sleep duration, quality of sleep”

    Human trialafter bilateral cataract surgery8 weeksn = 204

    Sleep and mood changes in advanced age after blue-blocking (yellow) intra ocular lens (IOLs) implantation during cataract surgical treatment: a randomized controlled trial

    Aging & mental health

What is blue-blocking intraocular lens linked with?

1

Studies link blue-blocking intraocular lens with 1 measure, most often depression (1 study).

Depression

upin humans1

1 study
  1. Blue-blocking intraocular lens raise the risk of depression in humans after bilateral cataract surgery (13.1% vs 4.7%, p = 0.02).

    “The rate of patients whose BDI score increased at the cutoff score of ≥5 after surgery was significantly higher in the yellow IOL group”

    Human trialafter bilateral cataract surgery8 weeksn = 204

    Sleep and mood changes in advanced age after blue-blocking (yellow) intra ocular lens (IOLs) implantation during cataract surgical treatment: a randomized controlled trial

    Aging & mental health

More on Depression

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