Vascular risk index
Vascular risk index has been studied in 1 paper since 2025: 1 observational study in people. The newest paper, May 25, 2025: “Association between vascular risk factors burden and neurodegenerative diseases: results from ONDRI”.
1 paper studies it4 findingsUpdated
See all 1 papers on vascular risk index
At a glance
The findings reach people, from one lab or study. 1 lab in 1 country.
“A higher VRI was significantly associated with MCI/AD (1.5-fold, p = 0.05), FTD (1.7-fold, p =0 .02), and CVD (2.6-fold, p < 0.005) cohorts.”
None of its findings points the other way.
- 1 lab in 1 country
- Funders: Academic Medical Organization of Southwestern Ontario and 4 more
- Humans1
What is vascular risk index linked with?
4Studies link vascular risk index with 4 measures, most often white matter integrity (1 study), cerebrovascular disease (1) and frontotemporal dementia (1).
White matter integrity
downin humans1
1 study
White matter integrity
downin humans1
Vascular risk index is associated with white matter integrity in humans (pooled sample) (macro p = 0.005; micro p = 0.003).
“High VRI was associated with reduced macro and microstructural white matter integrity in the pooled sample (macro: p = 0.005; micro: p = 0.003)”
Humanspooled samplewhite matter
Association between vascular risk factors burden and neurodegenerative diseases: results from ONDRI
Journal of neurology
Cerebrovascular disease
upin humans1
1 study
Cerebrovascular disease
upin humans1
Vascular risk index is associated with cerebrovascular disease in humans (2.6-fold, p < 0.005).
“A higher VRI was significantly associated with MCI/AD (1.5-fold, p = 0.05), FTD (1.7-fold, p =0 .02), and CVD (2.6-fold, p < 0.005) cohorts.”
Humans
Association between vascular risk factors burden and neurodegenerative diseases: results from ONDRI
Journal of neurology
Frontotemporal dementia
upin humans1
1 study
Frontotemporal dementia
upin humans1
Vascular risk index is associated with frontotemporal dementia in humans (1.7-fold, p =0 .02).
“A higher VRI was significantly associated with MCI/AD (1.5-fold, p = 0.05), FTD (1.7-fold, p =0 .02), and CVD (2.6-fold, p < 0.005) cohorts.”
Humans
Association between vascular risk factors burden and neurodegenerative diseases: results from ONDRI
Journal of neurology
Mild cognitive impairment/Alzheimer's disease
upin humans1
1 study
Mild cognitive impairment/Alzheimer's disease
upin humans1
Vascular risk index is associated with mild cognitive impairment/Alzheimer's disease in humans (1.5-fold, p = 0.05).
“A higher VRI was significantly associated with MCI/AD (1.5-fold, p = 0.05), FTD (1.7-fold, p =0 .02), and CVD (2.6-fold, p < 0.005) cohorts.”
Humans
Association between vascular risk factors burden and neurodegenerative diseases: results from ONDRI
Journal of neurology