Upf1+ hipsc-derived cardiomyocytes
1 paper2 findings
- 1 lab in 1 country
- Animals1
Outcomes
2Infarct size
downin mice1
1 study
Infarct size
downin mice1
Upf1+ hipsc-derived cardiomyocytes decrease infarct size in mice.
“Upf1+ hiPSC-CM transplantation significantly improved left ventricular function, reduced infarct size, enhanced donor cell retention, and increased proliferative activity”
Animalspost-myocardial infarctionheart3x10 5 cells4 weeksn = 10
AHA Scientific Sessions 2025 abstract3 Nov 2025
Left ventricular function
upin mice1
1 study
Left ventricular function
upin mice1
Upf1+ hipsc-derived cardiomyocytes improve left ventricular function in mice.
“Upf1+ hiPSC-CM transplantation significantly improved left ventricular function, reduced infarct size, enhanced donor cell retention, and increased proliferative activity”
Animalspost-myocardial infarctionheart3x10 5 cells4 weeksn = 10
AHA Scientific Sessions 2025 abstract3 Nov 2025
Latest
1 in 12 monthsAHA Scientific Sessions 2025 Abstract
Upf1 Lactylation Enhances the Regenerative Potency of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Experiments in 10 miceInterventions