Tritiated water

Intervention

1 paper3 findings

PubChemChEBI

  • 1 lab
  • Animals1

Outcomes

3

Age at mammary fibroadenoma onset

downin rats1

1 study
  1. Tritiated water decreases age at mammary fibroadenoma onset in rats.

    “The mean age for mammary fibroadenoma onset decreased with an increasing dose of radiation.”

    Animalsincreasing radiation dose in pregnant Sprague-Dawley ratsmammary glandduring pregnancyfemales

    Neoplastic and life-span effects of chronic exposure to tritium. I. Effects on adult rats exposed during pregnancy

    Journal of the National Cancer Institute1 Aug 1975

Lifespan

downin rats1

1 study
  1. Tritiated water shortens lifespan in rats (Postexposure lifespan reduced by 14%, 24%, and 22% at 66, 330, and 660 rads, respectively).

    “Postexposure life-spans for dams chronically exposed to 66, 330, and 660 rads during pregnancy were reduced by 14, 24, and 22%, respectively.”

    Animalspostexposure lifespan in Sprague-Dawley dams66, 330, and 660 rads cumulative whole-body radiationduring pregnancyfemales

    Neoplastic and life-span effects of chronic exposure to tritium. I. Effects on adult rats exposed during pregnancy

    Journal of the National Cancer Institute1 Aug 1975

Mammary fibroadenoma incidence

upin rats1

1 study
  1. Tritiated water increases mammary fibroadenoma incidence in rats.

    “Throughout their life-spans and at autopsy, the dams showed an increased incidence of mammary fibroadenomas at exposure to 330 and 660 rads.”

    Animalspregnant Sprague-Dawley ratsmammary gland330 and 660 rads cumulative whole-body radiationduring pregnancyfemales

    Neoplastic and life-span effects of chronic exposure to tritium. I. Effects on adult rats exposed during pregnancy

    Journal of the National Cancer Institute1 Aug 1975

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