Trichiurus lepturus protein

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funder: National Key Research and Development Program of China

Model organisms1

Outcomes

Gut microbiota dysbiosis

upin flies1

1 study

Trichiurus lepturus protein induces gut microbiota dysbiosis in flies.
“High-throughput sequencing showed gut microbiota dysbiosis”
Model organismshigh-oxidation-level protein (carbonyl content: 6.60 nmol/mL)
Dietary oxidized Trichiurus lepturus protein exacerbates aging in Drosophila melanogaster by disrupting metabolic homeostasis and gut microbiota
Food chemistry16 Jan 2026

Climbing ability

downin flies1

1 study

Trichiurus lepturus protein impairs climbing ability in flies.
“impaired climbing ability, cold stress resistance, reproductive capacity and antioxidant capacity”
Model organismshigh-oxidation-level protein (carbonyl content: 6.60 nmol/mL)
Dietary oxidized Trichiurus lepturus protein exacerbates aging in Drosophila melanogaster by disrupting metabolic homeostasis and gut microbiota
Food chemistry16 Jan 2026

Lifespan

downin flies1−45%

1 study

Trichiurus lepturus protein shortens lifespan in flies (-44.93%).
“significantly shortened lifespan by 44.93%”
Model organismshigh-oxidation-level protein (carbonyl content: 6.60 nmol/mL)
Dietary oxidized Trichiurus lepturus protein exacerbates aging in Drosophila melanogaster by disrupting metabolic homeostasis and gut microbiota
Food chemistry16 Jan 2026

Latest

1 in 12 months

Food Chemistry21 Jan

Dietary oxidized Trichiurus lepturus protein exacerbates aging in Drosophila melanogaster by disrupting metabolic homeostasis and gut microbiota

Experiments in fliesCellular homeostasis

Paper

Trichiurus lepturus protein

Outcomes

Latest

Dietary oxidized Trichiurus lepturus protein exacerbates aging in Drosophila melanogaster by disrupting metabolic homeostasis and gut microbiota

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