Transient reprogramming

Papers on transient reprogramming

7 papers1 new in 30 days

Saturday, October 10

Research SquareOct 10

Short reprogramming reverses blood stem cell aging in mice

Activating reprogramming factors for 16 days in old mice reduced DNA damage, improved blood reconstitution, and dampened transposable element activity.Activating reprogramming factors for 16 days in old mice reduced DNA damage, improved blood reconstitution, and dampened transposable element activity.

A blood stem cell with compact chromatin sits beside a gray cell with fragmented chromatin, beneath a laboratory mouse and near smaller blood cells.

Preprint: experiments in micePartial reprogramming

Monday, August 31

bioRxivAug 31

Transient reprogramming limits AP-1-associated chromatin opening and transposable element activation to preserve hematopoietic stem cell function during aging and stress

Preprint: experiments in micePartial reprogramming

Saturday, June 27

Basic Research in CardiologyJun 27

Functional rejuvenation of endothelial cell aging by transient reprogramming

Experiments in micePartial reprogramming

Monday, January 5

bioRxivJan 5

Awakening intracellular immunity for functional HIV cure

Preprint: experiments in miceBlood and immune system

Friday, August 2

Aging CellAug 2

Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements

Computational studyBiomarkers

Monday, December 18

bioRxivDec 18

Retroelement-Age Clocks: Epigenetic Age Captured by Human Endogenous Retrovirus and LINE-1 DNA methylation states

Preprint: study in peopleBiomarkers

Tuesday, March 24

Nature CommunicationsMar 24

Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells

Experiments in human cellsPartial reprogramming