Arthritis & Rheumatology
Tramadol linked to lower death and fracture risks than some opioids
For tramadol, death hazard ratios—comparisons of rates over time—were 0.93 versus codeine, 0.81 versus hydrocodone and 0.40 versus oxycodone.For tramadol, death hazard ratios—comparisons of rates over time—were 0.93 versus codeine, 0.81 versus hydrocodone and 0.40 versus oxycodone.
Cohort · 1,057,635 peopleFractures
Who was studied1,057,635 adults with osteoarthritis starting opioids
What changedDeath from any cause was lower with tramadol than oxycodone (hazard ratio 0.40)
The catchLonger-term death and fracture risks are missing from the reported results