Total sleep time

Total sleep time has been studied in 4 papers since 2022: 4 observational studies in people. The newest paper, May 4, 2023: “Disturbance of sleep maintenance, but not sleep duration, activates nuclear factor-κB and signal transducer and activator of transcription family proteins in older adults: sex differences”.

Intervention

4 papers study it2 findingsUpdated

See all 4

“greater amount of WASO (β = 0.39, p < 0.01), but not TST, was associated with higher levels of NF-κB”
Disturbance of sleep maintenance, but not sleep duration, activates nuclear factor-κB and signal transducer and activator of transcription family proteins in older adults: sex differencesSleep2023doi:10.1093/sleep/zsad130

None of its findings points the other way.

  • 2 independent labs in 1 country
  • Funders: National Institute on Aging and 3 more
  • Humans4

What did studies of Total sleep time find?

2

Studies of Total sleep time measured 2 outcomes; the most studied are NF-κB signaling (1 study) and navigation task performance (1).

NF-κB signaling

no changein humans1

1 study
  1. Total sleep time has no effect on NF-κB signaling in humans.

    “greater amount of WASO (β = 0.39, p < 0.01), but not TST, was associated with higher levels of NF-κB”

    Humanssleep diarysleep durationperipheral blood monocytic cellsn = 82

    Disturbance of sleep maintenance, but not sleep duration, activates nuclear factor-κB and signal transducer and activator of transcription family proteins in older adults: sex differences

    Sleep

More on NF-κB signaling

Navigation task performance

no changein humans1

1 study
  1. Total sleep time has no effect on navigation task performance in humans.

    “Total sleep time was not linearly associated with the navigation tasks (ps > .087).”

    Humanslinear association analysis

    Associations of environmental and lifestyle factors with spatial navigation in younger and older adults

    Journal of the International Neuropsychological Society : JINS

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