Thymosin

Thymosin has been studied in 1 paper since 1989: none in people yet, 1 in animals. The research so far is in animals. The newest paper, May 29, 2026: “Regarding IL-15 Plus Thymosin α1 Reduces Senescent Hepatic CD8+ T Cells in Hepatocellular Carcinoma via PI3K/AKT Suppression”.

1 paper studies it52 more mention it2 findingsUpdated Jul 1, 1989

1 lab in 1 country

Funder: Japan Society for the Promotion of Science

Animals1

What did studies of Thymosin find?

2

Studies of Thymosin measured 2 outcomes; the most studied are kidney disease (1 study) and lifespan (1).

Kidney disease

downin mice1

1 study

Thymosin protects against kidney disease in mice.
“administration of thymosin in B/WF1 mice resulted in amelioration of kidney disease and elongation of the mean life span.”
Animalsin autoimmune prone B/WF1 mice
Combined grafting of bone marrow and thymus, and sequential multiple thymus graftings in various strains of mice. The effect on immune functions and life span
Mechanisms of ageing and developmentJul 1, 1989

More on Kidney disease

Lifespan

upin mice1

1 study

Thymosin extends lifespan in mice.
“administration of thymosin in B/WF1 mice resulted in amelioration of kidney disease and elongation of the mean life span.”
Animalsin autoimmune prone B/WF1 mice
Combined grafting of bone marrow and thymus, and sequential multiple thymus graftings in various strains of mice. The effect on immune functions and life span
Mechanisms of ageing and developmentJul 1, 1989

Latest

5 papers in 12 months

ZenodoJun 6

Therapeutic Peptides: An Evidence-Tiered Survey Across Neuroplasticity, Anti-Ageing, Fitness, and Tissue Repair: A Critical Review

Preprint: reviewInterventions

Journal of Gastroenterology and HepatologyMay 29

Regarding IL-15 Plus Thymosin α1 Reduces Senescent Hepatic CD8+ T Cells in Hepatocellular Carcinoma via PI3K/AKT Suppression

CommentaryHepatocellular carcinoma

Journal of Gastroenterology and HepatologyMar 26

IL-15 Plus Thymosin α1 Reduces Senescent Hepatic CD8⁺ T Cells in Hepatocellular Carcinoma via PI3K/AKT Suppression

Experiments in miceHepatocellular carcinoma

International Journal of Molecular SciencesDec 11

Aging and Thymosin Alpha-1

ReviewInterventions

Nature CommunicationsNov 21

MRAP mediated adipocyte differentiation by thymic mesenchymal stromal cells contributes to thymic involution

Experiments in miceBlood and immune system

Stem Cell ReportsAug 16

Thymosin beta 4 as an Alzheimer disease intervention target identified using human brain organoids

Experiments in miceAlzheimer's disease

Advanced ScienceApr 25

Tβ4-Engineered ADSC Extracellular Vesicles Rescue Cell Senescence Through Separable Microneedle Patches for Diabetic Wound Healing

Experiments in animalsSkin

Cellular and Molecular NeurobiologyFeb 28

Single-Cell Analysis of Sex and Gender Differences in the Human Brain During Development and Disease

Computational studyMechanisms

Brain, Behavior, & Immunity - HealthJan 27

Indications for an antidepressive effect of thymosin alpha-1 in a small open-label proof of concept study in common variable immune deficiency patients with depression

Non-randomized trial in 5 peopleDepression

BMC BiologyOct 23

Thymosin β4 promotes zebrafish Mauthner axon regeneration by facilitating actin polymerization through binding to G-actin

Experiments in zebrafishMechanisms