Papers on thymidine

75 papers

Saturday, June 20

Nature Reviews Disease PrimersJun 20

HIV and antiretroviral therapy-related fat alterations

ReviewMechanisms

Paper

Wednesday, March 4

Experimental Cell ResearchMar 4

The role of lamin B receptor in the regulation of senescence-associated secretory phenotype (SASP)

Experiments in human cellsCellular senescence

Paper

Sunday, December 22

CellsDec 22

Early Stroke Induces Long-Term Impairment of Adult Neurogenesis Accompanied by Hippocampal-Mediated Cognitive Decline

Experiments in animalsMechanisms

Paper

Wednesday, March 6

DiabetesMar 6

Glucagon Receptor Antagonist-Stimulated α-Cell Proliferation Is Severely Restricted With Advanced Age

Experiments in miceInterventions

Paper

Tuesday, January 8

Mechanisms of Ageing and DevelopmentJan 8

Lamin B receptor (LBR) is involved in the induction of cellular senescence in human cells

Experiments in cellsMechanisms

Paper

Friday, November 16

Stem Cell ResearchNov 16

Limbal epithelial stem cell activity and corneal epithelial cell cycle parameters in adult and aging mice

Experiments in miceCell cycle regulation

Paper

Saturday, September 22

PLOS OneSep 22

Antiretroviral exposure and comorbidities in an aging HIV-infected population: The challenge of geriatric patients

Study in peoplePopulations

Paper

Wednesday, April 25

Toxicological SciencesApr 25

Prenatal Exposure to DEHP Induces Neuronal Degeneration and Neurobehavioral Abnormalities in Adult Male Mice

Experiments in animalsMechanisms

Paper

Thursday, March 15

Tissue & CellMar 15

Detection of cell proliferation in adults of the water bear Hypsibius dujardini (Tardigrada) via incorporation of a thymidine analog

Experiments in model organismsMechanisms

Paper

Tuesday, February 27

Clinical Infectious DiseasesFeb 27

The Role of Mitochondrial DNA Variation in Age-Related Decline in Gait Speed Among Older Men Living With Human Immunodeficiency Virus

Cohort study of 455 peoplePopulations

Paper

Friday, December 1

Human Molecular GeneticsDec 1

Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome

Experiments in miceRapamycin

Paper

Saturday, August 19

Journal of Physiology and PharmacologyAug 19

The role of mTOR inhibitors and HMG-CoA reductase inhibitors on young and old endothelial cell functions, critical for re-endothelialisation after percutaneous coronary intervention: an in vitro study

Experiments in human cellsmTOR inhibitors

Paper

Friday, April 28

Antiviral TherapyApr 28

Metabolic profiles of individuals switched to second-line antiretroviral therapy after failing standard first-line therapy for treatment of HIV-1 infection in a randomized, controlled trial

Trial in peopleInterventions

Paper

Monday, April 24

Nature MedicineApr 24

Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment

Experiments in miceOsteoarthritis

Paper

Tuesday, March 14

PLOS Computational BiologyMar 14

Modelling T cell proliferation: Dynamics heterogeneity depending on cell differentiation, age, and genetic background

Experiments in miceBlood and immune system

Paper

Tuesday, December 20

OncotargetDec 20

Germ cell-specific sustained activation of Wnt signalling perturbs spermatogenesis in aged mice, possibly through non-coding RNAs

Experiments in miceWnt/β-catenin signaling

Paper

Sunday, November 20

The ProstateNov 20

Low p16INK4a Expression in Early Passage Human Prostate Basal Epithelial Cells Enables Immortalization by Telomerase Expression Alone

Experiments in human cellsTelomerase and telomere maintenance

Paper

Saturday, November 12

Molecular PainNov 12

Preventing painful age-related bone fractures: Anti-sclerostin therapy builds cortical bone and increases the proliferation of osteogenic cells in the periosteum of the geriatric mouse femur

Experiments in miceBones and joints

Paper

Saturday, November 5

Journal of Hematology & OncologyNov 5

T cells in multiple myeloma display features of exhaustion and senescence at the tumor site

Case-control study in peopleCellular senescence

Paper

Saturday, July 23

Experimental Cell ResearchJul 23

Dual roles of ERK1/2 in cellular senescence induced by excess thymidine in HeLa cells

Experiments in human cellsCellular senescence

Paper

Saturday, June 25

Experimental Cell ResearchJun 25

Combinatorial effects of continuous protein synthesis, ERK-signaling, and reactive oxygen species on induction of cellular senescence

Experiments in human cellsMAPK/ERK signaling

Paper

Thursday, June 2

AngiogenesisJun 2

Association of endothelial proliferation with the magnitude of weight loss during calorie restriction

Non-randomized trial in 57 peopleDietary restriction

Paper

Sunday, April 10

Biochemical and Biophysical Research CommunicationsApr 10

Aberrant localization of lamin B receptor (LBR) in cellular senescence in human cells

Experiments in human cellsCellular senescence

Paper

Wednesday, October 8

The Journal of Biological ChemistryOct 8

Long term expression of Drosophila melanogaster nucleoside kinase in thymidine kinase 2-deficient mice with no lethal effects caused by nucleotide pool imbalances

Experiments in miceInterventions

Paper

Thursday, February 1

Cell ProliferationFeb 1

Generation of somatic cell hybrids for the production of biologically active factors that stimulate proliferation of other cells

Experiments in pig cellsInterventions

Paper

Saturday, January 1

Molecular and Cellular BiologyJan 1

Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: involvement of two silencing domains and effect of Ras

Experiments in human cellsMechanisms

Paper

Wednesday, December 1

Annals of the New York Academy of SciencesDec 1

Effect of dietary restriction on DNA synthesis in vitamin E-deficient rats

Experiments in ratsDietary restriction

Paper

Wednesday, January 1

Neuro Endocrinology LettersJan 1

Melatonin supplementation restores cellular proliferation and DNA synthesis in the splenic and thymic lymphocytes of old rats

Experiments in ratsMelatonin

Paper

Monday, March 1

Free Radical Biology & MedicineMar 1

Positive correlation between mammalian life span and cellular resistance to stress

Experiments in cellsMechanisms

Paper

Wednesday, May 1

Journal of Cell ScienceMay 1

Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage

Experiments in miceBiomarkers

Paper