AgingResearch.NewsJoin free

Thiadiazolidinones

Thiadiazolidinones has been studied in 1 paper since 2023: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Oct 20, 2023: “Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan”.

Intervention

1 paper studies it1 findingUpdated

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Institute on Aging and 3 more
  • Model organisms1

What did studies of Thiadiazolidinones find?

1

Studies of Thiadiazolidinones measured 1 outcome; the most studied are lifespan (1 study).

Lifespan

upin worms1

1 study

  1. Thiadiazolidinones extend lifespan in worms (15-30%).

    “These TDZD analogs also extended wild-type C. elegans lifespan by 15-30% (p < 0.001)”

    Model organismswild-type

    Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan

    Pharmaceuticals (Basel, Switzerland)

Latest

Related