Tetramethylpyrazine nitrone

Intervention

1 paper5 findings

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Model organisms1

Outcomes

5

Lipofuscin

downin worms1

1 study
  1. Tetramethylpyrazine nitrone decreases lipofuscin in worms.

    “concurrently impeding lipofuscin accumulation”

    Model organismsduring aging

    Tetramethylpyrazine nitrone delays the aging process of C. elegans by improving mitochondrial function through the AMPK/mTORC1 signaling pathway

    Biochemical and biophysical research communicationsJun 3, 2024

More on Lipofuscin

Mobility

upin worms1

1 study
  1. Tetramethylpyrazine nitrone improves mobility in worms.

    “TBN was observed to significantly enhance normal activities during aging in C. elegans, such as mobility and pharyngeal pumping”

    Model organismsduring aging

    Tetramethylpyrazine nitrone delays the aging process of C. elegans by improving mitochondrial function through the AMPK/mTORC1 signaling pathway

    Biochemical and biophysical research communicationsJun 3, 2024

NAD+

upin worms1

1 study
  1. Tetramethylpyrazine nitrone increases NAD+ in worms.

    “TBN elevated ATP and NAD+ levels in aging nematodes”

    Model organismsin aging nematodes

    Tetramethylpyrazine nitrone delays the aging process of C. elegans by improving mitochondrial function through the AMPK/mTORC1 signaling pathway

    Biochemical and biophysical research communicationsJun 3, 2024

More on NAD+

ATP

upin worms1

1 study
  1. Tetramethylpyrazine nitrone increases ATP in worms.

    “TBN elevated ATP and NAD+ levels in aging nematodes”

    Model organismsin aging nematodes

    Tetramethylpyrazine nitrone delays the aging process of C. elegans by improving mitochondrial function through the AMPK/mTORC1 signaling pathway

    Biochemical and biophysical research communicationsJun 3, 2024

More on ATP

Lifespan

upin worms1

1 study
  1. Tetramethylpyrazine nitrone extends lifespan in worms.

    “TBN extends lifespan of wild-type nematodes”

    Model organisms

    Tetramethylpyrazine nitrone delays the aging process of C. elegans by improving mitochondrial function through the AMPK/mTORC1 signaling pathway

    Biochemical and biophysical research communicationsJun 3, 2024

Latest