Telomerase overexpression

1. Telomerase overexpression extends lifespan in mice (substantially).

   “Overexpression of telomerase has been demonstrated to substantially extend the lifespan of mice.”

   Review

   Mutagenesis by RNA-containing telomerase holoenzyme complex or R-loops: a missing piece of the puzzle

   Preprint·Jun 26, 2022

1. Telomerase overexpression raises the risk of cancer in mice.

   “However, this treatment has a negative side, namely the increase of cancer risk.”

   Review

   Mutagenesis by RNA-containing telomerase holoenzyme complex or R-loops: a missing piece of the puzzle

   Preprint·Jun 26, 2022

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