TAT1-DEN
Intervention1 paper1 finding
- Animals1
Outcomes
1Cognitive function
upin mice1Very low certainty
1 study
Cognitive function
upin mice1Very low certainty
TAT1-DEN improves cognitive function in mice.
“Acute treatment with TAT1‐DEN restored hippocampal proteasome function and significantly improved cognitive performance in aged and AD‐model mice.”
Animalsacute treatment in aged and hAPP-J20 micehippocampus
Proteasome Activation as a Therapeutic Strategy to Rescue Cognitive Decline in Aging and Alzheimer’s Disease · AAIC 2025 abstract · 23 Dec 2025