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Tactile stimuli

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Foundation for the National Institutes of Health and 2 more
  • Model organisms1

Outcomes

1

Lifespan

downin worms1

1 study

  1. Tactile stimuli shortens lifespan in worms.

    “Worms subjected to dietary restriction are shorter-lived when they perceive tactile stimuli that mimic bacterial food and/or protective soil.”

    Model organismsunder dietary restriction

    Rewarding touch limits lifespan through neural to intestinal signaling

    Proceedings of the National Academy of Sciences of the United States of America23 Oct 2025

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