Spousal caregiving

1. Spousal caregiving impairs cognitive function in humans (OR = 0.68, 95% CI: 0.12-1.24, p = 0.017).

   “spousal care was negatively associated with Mini-Mental State Examination (MMES) scores (OR = 0.68, 95% CI: 0.12-1.24, p = 0.017)”

   Humanswith basic activity of daily living (BADL)/instrumental activities of daily living (IADL) limitations

   Caregiving Models and Cognitive Decline in Middle-Aged and Older Adults with Limitations in Activities of Daily Living: A CHARLS Cohort Study (2011-2020)

   Dementia and geriatric cognitive disorders·Jun 6, 2026

1. Spousal caregiving is associated with frailty index in humans.

   “Among females, compared to non-caregivers, spousal caregiving was significantly associated with the increased frailty index when adjusted by all covariates”

   Humansadjusted by all covariatesfemales

   Impact of spousal caregiving on frailty index: longitudinal evidence from China Health and Retirement Longitudinal Study

   Age and ageing·May 31, 2025

More on Frailty index

1. Spousal caregiving is associated with frailty progression in humans.

   “Multilevel analysis demonstrated a significant difference in the changes in frailty index over 12 years between caregivers and non-caregivers.”

   HumansCaregivers compared with non-caregivers12 years

   Impact of caregiving on frailty in older spousal caregivers: A retrospective cohort study

   Geriatric nursing (New York, N.Y.)·Aug 30, 2024

1. Spousal caregiving is associated with frailty in humans.

   “A significant correlation was found between spousal caregiving and frailty increase.”

   HumansOlder spousal caregivers

   Impact of caregiving on frailty in older spousal caregivers: A retrospective cohort study

   Geriatric nursing (New York, N.Y.)·Aug 30, 2024