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Sonnerachromone b

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Bagui Scholars Program of Guangxi Zhuang Autonomous Region and 2 more
  • Model organisms1

Outcomes

1

Lifespan

upin worms1+28%

1 study

  1. Sonnerachromone b extends lifespan in worms (Up to 27.5%).

    “Specifically, they extended the mean lifespan of C. elegans by up to 39.4, 27.5, and 35.8%, respectively.”

    Model organismscompound 2

    Sonnerachromones A-G, Antiaging Chromones from the Fruit of Mangrove Sonneratia apetala

    Journal of natural products28 Jul 2025

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