Social isolation/deprivation profile

1. Social isolation/deprivation profile is associated with incident severe disability in humans (OR 1.44 (95% CI 0.91–2.30); sHR 1.24 (95% CI 0.85–1.80)).

   “Relative to relative advantage, adjusted odds ratios (ORs) were 1.60 (95% confidence interval [CI] 1.04–2.47), 2.05 (1.49–2.84), and 1.44 (0.91–2.30), respectively.”

   HumansInitially ADL/IADL-independent Chinese adults; relative advantage reference; age- and sex-adjusted2011–2018n = 2,585

   Multidimensional social determinants of health profiles and incident severe disability and recovery among older Chinese adults: a longitudinal CHARLS study

   BMC geriatrics·12 Oct 2026

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