Sciadopitysin
- 1 lab in 1 country
- Funders: China Postdoctoral Science Foundation and 3 more
- Animals1
Outcomes
1Bone loss
downin mice1
1 study
Bone loss
downin mice1
Sciadopitysin decreases bone loss in mice.
“we identify a small compound sciadopitysin which attenuate the degradation of YBX1 and attenuate bone loss in old mice.”
Animalsbone
Orchestration of alternative splicing regulates bone marrow mesenchymal stem cells fate during aging
bioRxiv (Cold Spring Harbor Laboratory)May 29, 2022Preprint
Latest
Cell Proliferation
Decreased YB-1 expression denervates brown adipose tissue and contributes to age-related metabolic dysfunction
Experiments in animalsMechanisms
The EMBO Journal
Splicing factor YBX1 regulates bone marrow stromal cell fate during aging
Experiments in animalsMechanisms
bioRxiv
Orchestration of alternative splicing regulates bone marrow mesenchymal stem cells fate during aging
Preprint: experiments in miceBones and joints