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S-nitroso-n-acetylpenicillamine

Intervention

2 papers2 findings

PubChemChEBIMeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

  • 2 independent labs in 2 countries
  • Funder: National Institutes of Health
  • Animals1

Outcomes

2

Oocyte quality

upin mouse cells1

1 study

  1. S-nitroso-n-acetylpenicillamine improves oocyte quality in mouse cells (ZPDT: 35.1 ± 5.5 vs 46.3 ± 8.9s, OMD: 13.3 vs 75.0%, CG loss: 50.0 vs 93.3%, SM: 80.0 vs 14.3%).

    “When exposed to SNAP, RB AP significantly decreased (ZPDT: 35.1 ± 5.5 vs 46.3 ± 8.9s, OMD: 13.3 vs 75.0% and CG loss: 50.0 vs 93.3%) and SM improved (80.0 vs 14.3%).”

    Cellsin retired breeder mouse oocytesoocytefemales

    Chronological age enhances aging phenomena and protein nitration in oocyte

    Frontiers in endocrinologyDec 12, 2023

Neuronal survival

upin cells1

1 study

  1. S-nitroso-n-acetylpenicillamine improves neuronal survival in cells.

    “Furthermore, both CR sera and SNAP were capable of improving neuronal survival.”

    Cellsneurons

    Calorie restriction increases cerebral mitochondrial respiratory capacity in a NO•-mediated mechanism: impact on neuronal survival

    Free radical biology & medicineJan 28, 2012

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