S-1-propenyl-L-cysteine

S-1-propenyl-L-cysteine has been studied in 1 paper since 2026: 1 trial in people; 1 in the past year. The newest story, Oct 28, 2026: “Garlic compound increased muscle force in aged mice”.

Intervention

1 paper studies it2 findingsUpdated

PubChem

See all 1

“S1PC is also able to increase circulating eNAMPT levels in human individuals who maintain healthy adipose mass”
Garlic-derived metabolite activates LKB1, promotes adipose eNAMPT secretion, and improves age-related muscle function via hypothalamic signalingCell metabolism2026doi:10.1016/j.cmet.2026.04.006

None of its findings points the other way.

  • 1 lab in 1 country
  • 2 of 2 findings with company ties
  • Human trial1

What did studies of S-1-propenyl-L-cysteine find?

2

Studies of S-1-propenyl-L-cysteine measured 2 outcomes; the most studied are eNAMPT (1 study) and STK11 (1).

eNAMPT

upin humans1

1 study
  1. S-1-propenyl-L-cysteine increases eNAMPT in humans.

    “S1PC is also able to increase circulating eNAMPT levels in human individuals who maintain healthy adipose mass”

    Human trialin human individuals who maintain healthy adipose mass

    Garlic compound increased muscle force in aged mice

    Cell metabolism

More on eNAMPT

STK11

upin animals1

1 study
  1. S-1-propenyl-L-cysteine activates STK11.

    “S1PC significantly activates liver kinase B1 (LKB1) through enhancing its tertiary complex formation with STRAD and MO25”

    Animalswhite adipose tissue

    Garlic compound increased muscle force in aged mice

    Cell metabolism

More on STK11

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 1Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 01 paper in 12 months
Cell Metabolism

Garlic compound increased muscle force in aged mice

Experiments in aged mice traced the benefits to a protein released by fat tissue that targeted the hypothalamus, a brain region.Experiments in aged mice traced the benefits to a protein released by fat tissue that targeted the hypothalamus, a brain region.

Mouse studyMuscle