Regulatory t-cell supplementation

Intervention

1 paper1 finding

  • 1 lab in 1 country
  • Funders: National Institute of Child Health and Human Development and 1 more
  • Animals1

Outcomes

1

Digit-tip regeneration

upin mice1

1 study
  1. Regulatory t-cell supplementation improves digit-tip regeneration in mice.

    “CD4 + T-cell-mediated inhibition of regeneration was rescued by supplementation with T regulatory cells or recombinant RANKL, a mediator of osteoclast differentiation.”

    AnimalsCD4+ T-cell-mediated inhibition of regenerationdigit tip

    Some immune cells hindered digit-tip regrowth in mice

    NPJ Regenerative medicine13 Oct 2026

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NPJ Regenerative Medicine

Some immune cells hindered digit-tip regrowth in mice

Cell-transfer experiments in mice lacking lymphoid immune cells found that regulatory immune cells rescued regeneration inhibited by another immune-cell type.Cell-transfer experiments in mice lacking lymphoid immune cells found that regulatory immune cells rescued regeneration inhibited by another immune-cell type.

Experiments in miceImmune response