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Recombinant IGFBP2

Intervention

1 paper studies it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: British Heart Foundation and 1 more
  • Animals1

Outcomes

2

Pulmonary fibrosis

downin mice1

1 study

  1. Recombinant IGFBP2 decreases pulmonary fibrosis in mice.

    “intranasal delivery of recombinant IGFBP2 protects aged mice from weight loss and demonstrated antifibrotic effects after bleomycin lung injury”

    Animalsafter bleomycin lung injurylung

    Loss of IGFBP2 mediates alveolar type 2 cell senescence and promotes lung fibrosis

    Cell reports. MedicineFeb 13, 2023

More on Pulmonary fibrosis

Weight loss

downin mice1

1 study

  1. Recombinant IGFBP2 protects against weight loss in mice.

    “intranasal delivery of recombinant IGFBP2 protects aged mice from weight loss”

    Animalsafter bleomycin lung injurylung

    Loss of IGFBP2 mediates alveolar type 2 cell senescence and promotes lung fibrosis

    Cell reports. MedicineFeb 13, 2023

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