Potassium chloride
Potassium chloride has been studied in 5 papers since 2016: 1 trial in people, 4 in animals; 2 in the past year. It is an approved medicine.
See all 30 papers on potassium chloride
At a glance
The findings reach worms or flies, none yet in people. 3 independent labs in 2 countries; 9 trials, none about aging, 2 with no results posted.
None of its findings points the other way.
- 3 independent labs in 2 countries
- 9 trials, none about aging, 2 with no results posted
- Funders: National Institute on Aging and 7 more
- Animals4
What did lifespan studies of potassium chloride find?
DrugAgeDrugAge records 1 result from 1 paper: 1 in C. elegans. Average lifespan is the mean or the median, as each paper reports it.
What did studies of potassium chloride find?
2Studies of potassium chloride measured 2 outcomes; the most studied are calcium transients (1 study) and Psen1–Syt1 association (1).
Calcium transients
upin cells1
1 study
Calcium transients
upin cells1
Potassium chloride induces calcium transients in cells.
“these cells exhibited calcium transients in response to KCl, BayK, and capsaicin stimulation.”
Cellsinduced sensory neuron-like cells
Cells & development
Psen1–Syt1 association
upin mouse cells1
1 study
Psen1–Syt1 association
upin mouse cells1
Potassium chloride induces Psen1–Syt1 association in young and old neurons.
“Treatment with KCl triggered the interaction in both young and old neurons.”
Cellsin young and old neurons
Presenilin 1 increases association with synaptotagmin 1 during normal aging
Neurobiology of aging
Has potassium chloride been tested in people?
0 of 9 about agingYes: 1 trial in people have been published, and 9 trials are registered.
Approved
Apr 25, 1975Discontinued
May 22, 1980Discontinued
Jun 9, 1980Discontinued
Oct 17, 1980Discontinued
Apr 17, 1986Hypokalemia, metabolic alkalosis
Jun 13, 1986Discontinued
All 14Fewer
Repurposing
Phase 4Completed1 trial
Phase 4Completed1 trial
Phase 4Results posted1 trial
Phase 4Results posted1 trial
Phase 4Results posted1 trial
Phase 4Completed1 trial
All 8Fewer
Trial sponsors
1 trialPhase 4300 people
1 trialPhase 4143 people
1 trialPhase 440 people
Glostrup University Hospital, Copenhagen
1 trialPhase 425 people
Children's Hospital Medical Center, Cincinnati
1 trialPhase 419 people
Hospital de Clinicas de Porto Alegre
1 trialPhase 2/3128 people