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Polybrene

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Animals1

Outcomes

2

Mean survival time

no changein mice1

1 study

  1. Polybrene has no effect on mean survival time in mice.

    “However, the mean survival time was unchanged, and remained the same in leukaemic and non-leukaemic animals.”

    AnimalsAKR mice

    Life span, leukaemia and amyloid incidences of untreated and polycation-treated AKR mice

    British journal of cancer1 Jan 1978

Leukaemia incidence

downin mice1

1 study

  1. Polybrene decreases leukaemia incidence in mice.

    “By treating sucklings with the polycations diethylaminoethyl-dextran or hexadimethrine bromide the leukaemia incidence was significantly reduced.”

    AnimalsAKR mice

    Life span, leukaemia and amyloid incidences of untreated and polycation-treated AKR mice

    British journal of cancer1 Jan 1978

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