Plant-derived virus-like particle influenza vaccine

1. Plant-derived virus-like particle influenza vaccine increases immune response in mice.

   “Both CD4+(TNFα, IFNγ) and CD8+ (IFNγ) T cell responses were also greater in the H1-VLP group than the IIV.”

   Animalscompared to IIVspleen3μg42 daysfemales

   A plant-derived VLP influenza vaccine elicits a balanced immune response even in very old mice with co-morbidities

   PloS one·10 Jan 2019

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1. Plant-derived virus-like particle influenza vaccine increases ELISA titres in mice (GMT 961 vs 425, p = 0.03).

   “ELISA titres were significantly higher in the H1-VLP animals compared to the IIV group (GMT (95% CI): 961 (427, 2163) vs 425 (200, 903): p = 0.03).”

   Animalscompared to IIVserum3μg42 daysfemales

   A plant-derived VLP influenza vaccine elicits a balanced immune response even in very old mice with co-morbidities

   PloS one·10 Jan 2019

More on ELISA titres