Pharmacological partial reprogramming

Intervention1 paper3 findings

  • Animals1

Outcomes

3

Reactive oxygen species

downin mouse cells1Very low certainty

1 study
  1. Pharmacological partial reprogramming decreases reactive oxygen species in mouse cells.

    Cellsin replicatively senescent ECsreprogramming cocktailendothelial cell

    Transient pharmacological reprogramming reverses endothelial senescence and promotes vascular regeneration · AHA Scientific Sessions 2025 abstract · 3 Nov 2025

Reactive oxygen species →

Angiogenesis

upin mouse cells1Very low certainty

1 study
  1. Pharmacological partial reprogramming improves angiogenesis in mouse cells.

    Cellsin replicatively senescent ECsreprogramming cocktailendothelial cell

    Transient pharmacological reprogramming reverses endothelial senescence and promotes vascular regeneration · AHA Scientific Sessions 2025 abstract · 3 Nov 2025

Angiogenesis →

Cellular senescence

downin mouse cells1Very low certainty

1 study
  1. Pharmacological partial reprogramming decreases cellular senescence in mouse cells.

    Cellsin replicatively senescent ECsreprogramming cocktailendothelial cell

    Transient pharmacological reprogramming reverses endothelial senescence and promotes vascular regeneration · AHA Scientific Sessions 2025 abstract · 3 Nov 2025

Cellular senescence →

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